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Human il-2 uniprot

WebMay 23, 2024 · Cryo-EM structures of 11-2 F / MTA-bound human PRMT5/MEP50 complex and its apo form resolved at 3.1 and 3.2 Å respectively show that 11-2 F in the catalytic pocket shifts the cofactor-binding pocket away by ~2.0 Å, contributing to positive cooperativity. ... 2.1.1.320: UniProt & NIH Common Fund Data Resources: Find proteins … WebApr 9, 2024 · This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine …

Q0GK43 - UniProt

WebInterleukin-2, T-cell growth factor, IL2_HUMAN. UniProt Code History. P60568. Gene. IL2, IL-2, TCGF, lymphokine. Bioactivity. The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Purification Method. SDS-PAGE & HPLC >= 98% WebJul 2, 2002 · 1M47 Crystal Structure of Human Interleukin-2 PDB DOI: 10.2210/pdb1M47/pdb Classification: CYTOKINE Organism (s): Homo sapiens Expression System: Escherichia coli BL21 Mutation (s): No Deposited: 2002-07-02 Released: 2002-07-31 taylor doty https://crs1020.com

Human IL-2 Recombinant Protein (PHC0021)

WebRecombinant human IL-2 is a non-glycosylated protein containing 134 amino acids. Recombinant human IL-2 has a Ser substitute for Cysteine at position 126. Reconstitute using sterile 10 mM HCl at 0.1 mg/mL and … WebOct 3, 2006 · Function. Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal … WebHuman IL-2 acts on murine and human T cells, and its receptors are shared by others cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with IL-15 and the γ … taylor dome wedding dress

IL13RA2 protein expression summary - The Human Protein Atlas

Category:3558 - Gene ResultIL2 interleukin 2 [ (human)] - National Center …

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Human il-2 uniprot

(130-097-745) Human IL-2 IS, premium grade - CiteAb

WebRecombinant human Interleukin-2 (IL-2) is expressed in human HEK 293 cells with a calculated molecular mass of 15 kDa. This protein is manufactured in human cells, ... Endotoxin: 1.00 EU/µg IL-2 (LAL) Uniprot: P60568 Precautions and Disclaimer For R&D use only. Not for drug, household, or other uses. Please consult the Safety Data Sheet for WebLess than 0.01 ng endotoxin/1 μg hIL-2. Activity. The bioactivity of recombinant hIL-2 was determined in a CTLL-2 cell proliferation assay. The ED 50 of each lot is between 0.1 - …

Human il-2 uniprot

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WebHuman IL-2 is synthesized as a 153-amino-acid precursor polypeptide and is then processed to mature IL-2. Mature human IL-2 is a 15.5 kDa four-alpha-helix bundle glycoprotein that consists of 133 amino acids. WebUseful information about the gene from Entrez. The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This p rotein binds …

WebInterleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and … WebDescription. Interleukin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 133 amino acids fragment (21-153) having a …

Web(130-097-745) Human IL-2 IS, premium grade Sign in or register to save this reagent to your favourites Supplier Miltenyi Biotec Classification Cytokine Protein Name Interleukin-2 UniProt ID P60568 - IL2_HUMAN Species Homo sapiens (Human) Gene IL2 View Product On Supplier's Website Request a Quote from Miltenyi Biotec Supplier provided information WebHuman, recombinant IL-2 has the same biological activity in vitro as compared to human, natural IL-2 (15, 1–4). Interleukin-2 (IL-2, also known as T-Cell Growth Factor, TCGF) is …

WebInterleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages.

WebJul 2, 2002 · Total Structure Weight: 15.63 kDa Atom Count: 1,055 Modelled Residue Count: 122 Deposited Residue Count: 133 Unique protein chains: 1 Display Files Download … taylor door west branch miWebApr 4, 2024 · Tat. tat. HIV-1 Tat upregulates the expression of interleukin 15 (IL15) gene in mammary epithelial cells. PubMed. capsid. gag. Unactivated memory CD4+ T cells infected by HIV-1 in the presence of IL-2 and IL-15 alone or IL-6/IL-7/TNF-alpha combination, upregulate granzyme B and HIV-1 CA production. taylor door company paterson njWebSep 17, 2024 · The present invention relates to a pharmaceutical composition for enhancing immunity, and was arrived at by discovering that oligopeptide AQTGTGKT and an analog thereof have the effect of appropriately modulating immune activity in the body, such as by suppressing excessive immune response while enhancing immune activity for defending … the engine inn walbottle menuWebIL-2, Human Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. taylor dooley lavagirl photos and picturesWebProteini. Full gene name according to HGNC. Interleukin 13 receptor subunit alpha 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. IL13RA2 (CD213a2, CT19, IL-13R, IL13BP) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. taylor dorothyWebProduct name Recombinant human IL-2 protein (Active) See all IL-2 proteins and peptides Biological activity The ED 50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10 5 units/mg. Purity > 95 % SDS-PAGE. Endotoxin level < 1.000 Eu/µg Expression system taylor dooley age 2005WebRecombinant Mouse IL-2 (Catalog # 402-ML) stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED 50 for this effect is 0.1-0.4 ng/mL. SDS-PAGE View Larger. 1 μg/lane of Recombinant Mouse IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a band (s) at 19 kDa. taylor dorothea drummer