Kif1c mouse
Web6 jul. 2024 · Like VPS15, KIF1C partially associates with GM130, and KIF1C depletion using CRISPR/Cas9 in HEK293T cells resulted in GA dispersal into small vesicles. …
Kif1c mouse
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WebFor example, C3H mouse macrophages lysed by LeTx at 1 ng/ml are 100,000 times more sensitive than A/J mouse macro-phages (5). Macrophages from CBA/J and BALB/c … Web1 feb. 2010 · We established Kif1c knockout mice with LT-sensitive 129/Sv-derived embryonic stem cells followed by 13 backcrosses with LT-resistant C57BL/6J mice (B6) …
Web30 dec. 2024 · Podosome formation in osteoclasts is an important initial step in osteoclastic bone resorption. Mice lacking c‐Src (c‐Src −/−) exhibited osteopetrosis due to a lack of podosome formation in osteoclasts.We previously identified p130Cas (Crk‐associated substrate [Cas]) as one of c‐Src downstream molecule and osteoclast‐specific … WebThe kinesin-like motor protein KIF1C occurs in intact cells as a dimer and associates with proteins of the 14-3-3 family. Dorner, C., Ullrich, A., Häring, H.U., Lammers, R. J. Biol. Chem. (1999) [ Pubmed] Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum.
Web26 okt. 2024 · Mutation analysis of KIF1A in the ALS cohorts. To identify the possible association of KIF1A with ALS, we analyzed the WES data from 941 patients with ALS. Demographic and clinical characteristics are shown in Table 1.In this cohort, eight different candidate heterozygous RDVs in the KIF1A gene were identified in 10 unrelated … Webprotein-coding gene in the species Mus musculus. Kif1c (Q18251833) Q18251833)
Web8 dec. 2024 · Intracellular transport: KIF1C produces force along with a few slips. Force generation of KIF1C is impaired by pathogenic mutations. c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells. Whole exome sequencing identified a homozygous KIF1C variant in both patients
WebSymbol: Kif1c: Name: kinesin family member 1C: RGD ID: 731800: MGI Page: MGI: Description: Predicted to enable ATP hydrolysis activity; microtubule binding activity ... tappi test method t425WebKif1c Mouse Gene Details kinesin family member 1C International Mouse Phenotyping Consortium Gene: Kif1c MGI:1098260 Not currently registered for phenotyping at IMPC Phenotyping is currently not planned for a knockout strain of this gene. Gene Summary Name: kinesin family member 1C Synonyms: Orch3, D11Bwg1349e, N-3 kinsin, … tappi test method t559WebGene target information for Kif1c - kinesin family member 1C (house mouse). Find diseases associated with this biological target and compounds tested against it in bioassay … tappiann hopkins facebookWebInvestigation on Hereditary spastic paraplegia type 58 (HSP 58): Conducted a study on KIf1C's mutation in two new transgenic mice models in collaboration with a team from the INRAE laboratory Clinical Pharmacist ... Thesis: "KIF1C and demyelination: Analysis of V5 tagged Kif1c transgenic mice" tappi young professionalWebKIF1C (human): S676‑p, KIF1C (mouse): S676‑p, KIF1C (rat): S673‑p Characterization Methods used to characterize site in vivo : mass spectrometry tappi test methods t213 and t437WebKinesin-like protein KIF1C is a protein that in humans is encoded by the KIF1C gene.[5][6] Kif1C is a fast, plus-end directed microtubule motor.[7] It takes processive 8nm steps … tappi test method t411Web(F) The MVD was calculated by counting the number of vessels per field of each tumor in each mouse analyzed. The total numbers of fields scored are as follows: RT2 controls: 75 fields from nine mice; CtsB -/- RT2: 70 fields from nine mice; CtsS -/- RT2: 41 fields from seven mice; CtsL -/- RT2: 25 fields from four mice; CtsC -/- RT2: 37 fields from three mice. tappi trade shows