Multidrug and toxin extrusion transporter
Web2 sept. 2015 · Ito, S. et al. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the ... Web2 sept. 2016 · Multidrug and toxin extrusion 1 (MATE1), encoded by the solute carrier family 47, member 1 ( SLC47A1) gene, was identified as an H + -coupled organic cation exporter [ 11 ]. This transporter is mainly expressed on the luminal membranes of the renal urinary duct [ 12 ].
Multidrug and toxin extrusion transporter
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Web4 ian. 2024 · The multidrug and toxin extrusion (MATE) transporter family comprises 70 members in the Medicago truncatula genome, and they play seemingly important, … Web12 apr. 2024 · The target drug transporters assessed were P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), organic anion transporting polypeptide (OATP) 1B1, …
Web1 nov. 2024 · In conclusion the MATE transporter DTX30 modulates auxin levels in the root to regulate cell elongation and also promotes citrate exudation to alleviate Al toxicity. … Web1 mar. 2009 · Recently, a multidrug and toxin extrusion (MATE) transporter protein family was identified, assigned as the SLC 47 family ( 12, 13 ). The SLC47A1 gene, with gene location 17p11.2, encodes the MATE1 transporter. Metformin is one of the substrates of this transporter ( 14 ).
Web1 feb. 2014 · Human multidrug and toxic compounds extrusion transporter 1 (hMATE1/SLC47A1) is a H (+)-coupled organic cation exporter responsible for the final step of excretion of various xenobiotics at... Weband the multidrug and toxin extrusion (MATE) transporters. MATE belongs to the SLC47 transporter family consisting of only two members, MATE1 and MATE2-K. MATE2-K
Web9 ian. 2009 · H + /organic cation antiporters (multidrug and toxin extrusion: MATE1 and MATE2-K) play important roles in the renal tubular secretion of cationic drugs. We have recently identified a regulatory...
Web13 iun. 2013 · Genetic studies indicated that the multidrug and toxin extrusion transporter ENHANCED DISEASE SUSCEPTIBILITY5 (EDS5) of Arabidopsis ( … trs in sapWeb9 mai 2012 · The organic cation transporter, solute carrier (SLC) 22A2/organic cation transporter (OCT) 2, is highly expressed in the basolateral membrane of proximal tubules and is considered the predominant transporter … trs in cancunWeb27 feb. 2024 · MtMATE69 is a citric acid transporter induced by Fe-deficiency. Overexpression of MtMATE69 in hairy roots altered Fe homeostasis and hormone levels under Fe-deficient or Fe-oversupplied conditions. MtMATE66 is a plasma membrane citric acid transporter primarily expressed in root epidermal cells. trs instituteWeb26 apr. 2012 · organic cation transporter 3, multidrug and toxin extrusion transporter 1, placenta, pregnancy, pharmacokinetics, MPP +. Topic: fetus maternal-fetal exchange membrane transport proteins mothers toxins kidney pharmacokinetics placenta rats fetoplacental circulation maternal circulation organic cation transporter 3 Issue Section: … trs indexWeb1 apr. 2024 · Multidrug and toxic compound extrusion (MATE) transporters are primarily expressed in the kidneys and liver, where they contribute to the excretion of organic cations. Our previous study suggested that pig MATE2 (class III) participates in testosterone secretion from Leydig cells. trs inboxxWeb29 aug. 2014 · So far, the number of polymorphisms in SLC22A1, SLC22A2, and SLC47A1 genes coding for organic cation transporter 1 (OCT1), OCT2, and multidrug and toxin extrusion transporter 1 (MATE1) metformin ... trs in taxesWeb27 ian. 2024 · Members of multidrug and toxin extrusion (MATE) transporters are imparted in the secondary metabolites transportation. ... Export of salicylic acid from the … trs in sugar