2024 Promis-hfpef研究

Promis-hfpef研究

Author: zmyz

August undefined, 2024

WebJan 7, 2024 · According to recent epidemiologic data, approximately 50% of patients with heart failure (HF) have HF with preserved ejection fraction (HFpEF). Hypertension, obesity, … Web入选中国住院患者心力衰竭注册研究（cn-hf）中符合hfpef诊断标准的患者，根据随访期间是否死亡分为死亡组和存活组。从CN-HF中获得研究对象的人口学信息、入院时体格检查信息、入院首次超声心动图检查结果、实验室检查结果、合并症情况、用药情况和临床 ...

Prevalence and correlates of coronary microvascular dysfunction in

Web综上所述，该研究构建了一种全新的hfpef小鼠模型，高度复制了临床hfpef患者的病理表型。以此为基础，揭示NLRP3炎症小体和线粒体功能障碍是HFpEF发生发展的重要驱动因素，并证实提升酮体β-OHB水平可调控上述线粒体-炎症环路，改善HFpEF症状（图6）。 WebBackground: Coronary microvascular dysfunction (CMD) is common in heart failure with preserved ejection fraction (HFpEF). We assessed the association of CMD with hospitalization and mortality in HFpEF. Methods and results: We assessed the 1-year outcomes in patients from the PROMIS-HFpEF study, a prospective observational study of … sup-wald检验

Why do we care about coronary microvascular dysfunction and …

WebThe PROMIS-Plus-HF measure comprises 86 items (64 existing; 22 new) across 18 domains. Internal consistency reliability (Cronbach α) coefficients ranged from 0.52 to 0.96, with … WebNov 1, 2024 · Methods and Results. We assessed the 1-year outcomes in patients from the PROMIS-HFpEF study, a prospective observational study of patients with chronic stable HFpEF undergoing coronary flow reserve measurements. Outcomes were (1) time to cardiovascular (CV) death/first HF hospitalization, (2) CV death/recurrent HF … WebJun 29, 2024 · Recently, they defined a unique LA myopathy phenotype in HFpEF in the PROMIS-HFpEF observational study by taking the residuals of linear regression of LA … sup-wald test

Lipotoxicity: a driver of heart failure with preserved ejection ...

Promis-hfpef研究

WebNov 30, 2024 · The non-phenomapping literature in HFpEF has importantly identified that regional adiposity and abdominal visceral and/or epicardial adipose tissue may be critical to the pathophysiology and outcomes of patients with HFpEF, compared to simply total body mass index, in USA and European cohorts. 48–51 In Asia, this cardiometabolic phenotype … Web来自专栏： uPAR文献精读共6篇a 。。 ...

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WebMar 14, 2024 · ROS Navigation是一个ROS软件包，用于实现机器人的导航功能。. 它包含了一系列的算法和工具，可以帮助机器人在未知环境中进行自主导航。. ROS Navigation的源码详解主要包括以下几个方面： 1. Costmap 2D：这是ROS Navigation中的一个重要组件，用于生成机器人周围的地图 ... WebOct 14, 2024 · Among 192 with blood samples available of the original 202 patients with a validated diagnosis of HFpEF (LV ejection fraction ≥40% without unrevascularized …

WebConclusions PROMIS-HFpEF is the ﬁrst prospective multi-centre, multinational study to demonstrate a high prevalence of CMD in HFpEF in the absence of unrevascularized … WebMay 13, 2024 · Consecutive steps of the comorbidity-inflammation paradigm were recently evaluated in the PROMIS-HFpEF study (PRevalence Of Microvascular dySfunction in HFpEF), 8 which performed a mediation analysis based on associations of comorbidities with cardiac structure/function, of comorbidities with inflammation and of inflammation with …

WebJun 24, 2024 · Based on invasive coronary angiography, three main conditions were identified: 1) obstructive epicardial CAD, 2) endothelium-independent CMD (by physiologic testing), and 3) endothelium-dependent CMD (by vasoreactivity testing). Based on CMRI, three main conditions were identified: 1) impaired myocardial perfusion, 2) myocardial … WebWe analyzed blood samples and data from the PROMIS-HFpEF study (Prevalence of Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction), the design of which has been described previously.10 In brief, PROMIS-HFpEF was a multicenter, observational study to evaluate the prevalence and correlates of coronary microvascular …

WebIn the PROMIS-HFpEF study, echocardiographic measurement of CFR in the left anterior descending coronary artery identified CMD in 75% of the participants, using a CFR …

WebSep 25, 2024 · PROMIS-HFpEF is the first prospective, multicenter, multinational study to show that coronary microvascular dysfunction is really prevalent in prospective HFpEF. supa award sunderland universityWebNov 24, 2024 · Methods: In 228 patients with HFpEF from the multicenter PROMIS-HFpEF study (Prevalence of Microvascular Dysfunction in Heart Failure With Preserved Ejection … supa 6 port niger feeder with trayWebSep 20, 2024 · 本项研究推导并验证了一个简单的attr-cm评分，来预测hfpef患者为attr-cm的风险。作者：王崇慧. 来源：北一心语. 研究方法. 本研究对2013年5月10日至2024年8月31日在明尼苏达州罗切斯特市梅奥诊所的666名hf（ef≥40%）和疑似attr-cm患者进行回顾性队列研 … supa awesome mailflow testerWebOct 13, 2024 · Abstract. Heart failure with preserved ejection fraction (HFpEF) is a growing public health concern, with rising incidence alongside high morbidity and mortality. However, the pathophysiology of HFpEF is not yet fully understood. The association between HFpEF and the metabolic syndrome (MetS) suggests that dysregulated lipid metabolism could … supa aquatics supplies ltd holbrookWebAim: Epicardial adipose tissue (EAT) may play a role in the pathophysiology of heart failure with preserved ejection fraction (HFpEF). We investigated associations of EAT with proteomics, coronary flow reserve (CFR), cardiac structure and function, and quality of life (QoL) in the prospective multinational PROMIS-HFpEF cohort. supa bathroom dealzWebJun 10, 2015 · PROMIS: Clinical Outcomes Assessment - Funded Research. The NIH Common Fund was enacted into law by Congress through the 2006 NIH Reform Act to … supa bird foodWebNov 1, 2024 · In the multi-national PRevalence Of MIcrovascular dySfunction in Heart Failure with Preserved Ejection Fraction (PROMIS-HFpEF) study we demonstrated that 75% of HFpEF patients have CMD defined as a coronary flow reserve of <2.5. 10 In this exploratory study, we report the association between CMD and outcomes and quality of life. Methods supa bilingual therapy services